A detailed aanalysis of diphosphate binding sites in proteins
نویسندگان
چکیده
منابع مشابه
Metal Binding Sites in Proteins
Metal ions play a critical role in living systems. About one third of proteins need to bind metal for their stability and/or function. In this review, current sequence based and structure based methods for metal binding site prediction will be presented, with emphasis on the CHED and SeqCHED methods of prediction from apo-protein structures and protein sequences having homologs (even remote) in...
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Metal-binding sites have been engineered into both de novo designed and naturally occurring proteins. Although the redesign of existing metal-binding sites in naturally occurring proteins still offers the most promise for a successful design, the more challenging goal of engineering metal-binding sites in de novo designed proteins and peptides is being achieved with increasing frequency. Creati...
متن کامل5'-Phosphate-Binding Sites in Proteins
many enzymic reactions. Almost all these pyridoxal phosphate-dependent enzymes have an absorption band around 415nm, although most of them have higher peaks at 335 nm. The studies made with simple models have shown that the 415nm band is due to a Schiffbase in a hydrophilic medium [structure (I) of Scheme 1] (Matsushima & Martell, 1967). The 335nm band can be assigned either to the structure (I...
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Drosophila homeotic genes and their vertebrate cognates, the Hox genes, encode homeodomain proteins that are thought to control segment-specific morphogenesis by regulating subordinate target genes. Although expression of many genes is thought to be influenced by homeotic/Hox function, little is known about the genes they directly regulate in the developing embryo. One of the Drosophila homeoti...
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Proteins and RNA interaction have vital roles in many cellular processes such as protein synthesis, sequence encoding, RNA transfer, and gene regulation at the transcriptional and post-transcriptional levels. Approximately 6%-8% of all proteins are RNA-binding proteins (RBPs). Distinguishing these RBPs or their binding residues is a major aim of structural biology. Previously, a number of exper...
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ژورنال
عنوان ژورنال: Chemistry Central Journal
سال: 2009
ISSN: 1752-153X
DOI: 10.1186/1752-153x-3-s1-p7